Lamelle Pharmaceuticals launches Matricoll ECM

A next-generation peptide-based oral supplement for comprehensive skin regeneration

Lamelle Pharmaceuticals is redefining the skincare supplement category with the launch of Matricoll ECM® a premium, science-driven oral anti-ageing supplement engineered to repair, rebuild, and protect the skin from within. Leveraging advanced bio-active peptide technology, Matricoll ECM® offers a multi-targeted approach to extracellular matrix (ECM) regeneration, setting a new benchmark for efficacy in ingestible skincare.

Skin ageing is characterised by the progressive breakdown of the ECM, the structural network composed primarily of collagen, elastin, and hyaluronic acid (HA). While typical oral supplements rely mainly on hydrolysed collagen, these larger peptides are often poorly absorbed, with only an estimated 10 - 30% reaching systemic circulation. This limited bioavailability often translates into incomplete or delayed skin benefits.

Matricoll ECM® overcomes these limitations through a sophisticated combination of highly bioavailable peptides and synergistic actives, including collagen tri- and di-peptides, elastin di-peptides, low-molecular-weight hyaluronic acid, astaxanthin, and niacinamide. This multi-layered, ECM-focused strategy supports accelerated skin repair, reduces inflammation, combats oxidative stress, and reinforces the skin barrier. Clinical evaluations demonstrate improvements in hydration, elasticity, wrinkle depth, and overall radiance, with superior absorption and potency compared to conventional collagen supplements.

A new benchmark in ingestible skin science through comprehensive extracellular matrix (ECM) restoration supported by research-grade peptide technology. Designed for efficiency and ease of use, the formulation offers convenient dosing while providing results comparable to procedural interventions, without downtime, invasiveness, or recovery. Its advanced bio-active peptides are engineered for direct absorption and remain effective even in the presence of gut microbiome imbalance, ensuring consistent, predictable outcomes. Beyond visible skin renewal, the systemic benefits extend to overall cellular resilience and metabolic support. Clinical data demonstrates measurable improvements, including up to a 25% increase in elasticity, 30–40% boost in hydration, 20% reduction in wrinkle depth, 20 - 30% enhancement in dermal density, and a 15 - 20% improvement in complexion luminosity. These accelerated, high-impact results are driven by innovative peptide science that elevates oral skin supplementation to a new level of performance.

What can you expect to see on your skin?

• Noticeably smoother, firmer, more resilient skin with improved elasticity and bounce
• Rebuilt skin structure promoting regeneration and delayed ageing
• A healthier, more youthful complexion protected from environmental damage
• Revitalised, hydrated, radiant skin due to improved cellular activity and metabolism
• Enhanced results from existing skincare and professional treatments through deeper skin receptivity

“Ingestible beauty has historically focused on collagen in isolation, but ageing is a whole-ECM phenomenon. Matricoll ECM® shifts the paradigm by delivering coordinated biological signals that stimulate collagen, elastin, and hyaluronic acid production simultaneously,” says Dr Bradley Wagemaker, Medical Director and Product Formulator, Lamelle Pharmaceuticals. “For the first time, we can offer a supplement that mirrors the sophistication of in-clinic interventions, giving patients a scientifically validated way to rebuild skin from its foundational matrix outward.”

Matricoll ECM® is now available through select skincare professionals, Lamelle Pharma Shop online, aesthetic clinics, and authorised retailers.

Repair. Rebuild. Protect. Choose Matricoll ECM® because real, lasting results begin deeper than the skin surface.

For more information visit: https://www.lamellepharmaceuticals.co.za/