Early-onset cancer risk

JOHANNESBURG, March 22nd, 2024 – There has been a marked increase in early onset cancer, particularly amongst Millennials. Age-risk factors have lowered from an average age of fifty years, two decades ago, to an alarming and emerging group, twenty-five- to twenty-nine-year-olds, where cancer rates have risen faster than other age groups (1).

“While the risk of contracting cancer remains more prevalent in an older age group, the growth in younger people contracting the condition is telling,” said Vanessa Snow, Head of Medical Affairs at Janssen South Africa. The American Cancer Society predicted that this year, seven percent of deaths and thirteen percent of colorectal cancers, for example, will be detected in persons under fifty years old. (2) It is out of the norm.

Snow said that studies are presently underway to understand the sustained upward movement in incidences of colorectal cancer. (2) “There has been upward movement, with momentum, and could almost be paralleled with the growing use of plastic in almost every aspect of our lives. In turn, this has caused growth in incidences of micro and nano-plastics in foodstuffs and water as a consequence,” said Snow. (3) And while the way these tiny particles are consumed and move through the human body is not understood properly yet, it is important to interrogate, particularly because of the potential links with cancer. (3)

Other cancers that are afflicting younger victims include breast, kidney, pancreas, and liver, amongst others. (4) Snow believes that the growth in colorectal cancer amongst younger people could be a direct consequence of a bloated western lifestyle. (4) “We are becoming more sedentary, our diets have moved too far in the direction of processed foods, and in many ways, that is how Millennials have grown up, in the age where fast food and processed products have come into its own, likely to the detriment of collective wellness.”

A sustained and growing upward trend in western obesity has also not helped (4), said Snow, which are also a consequence of diet, but also excessive consumption. “Add to that, the pollutants that have permeated across every aspect of the human environment, and the elements conducive to cancer risk factors present themselves in plain sight,” she said.

To this end, lifestyle changes and preventative wellness measures that healthcare professionals have shared through the years remain pertinent. Snow said that it should be reinforced amongst younger persons. “A healthy lifestyle that includes more unprocessed foods, fruit and vegetables, exercise and limited consumption of alcohol, cutting out vices like smoking; these are the simple rules of thumb that can be the difference between a longer, healthier life or contracting cancer,” she said. (5) Avoidance of risky behaviours like unprotected sex, self-care such as frequent self-examinations and regular visits to healthcare practitioners for screenings remain important weapons in a cancer-free arsenal, noted Snow.

“Managing external factors and impacts of environmental pollutants cannot be undone overnight,” said Snow, “but we are able to manage our wellness through the actions we take as individuals. From lifestyle and diet through to individual repurposing or recycling of single-use plastics. That, coupled with the significant advances that science is making in combating cancer, could bode well for a healthier future.”

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Sources:

1. Financial Times. The unexplained rise of cancer among millennials. https://www.ft.com/content/90d5f2e3-d539-4149-a503-2114ac3ef355?accessToken=zwAF_6nHrr24kdOQ1fLj1TlBSdOlAyEUrD7zVQ.MEYCIQC5hLVu40wMcEAuCJB0ND2aWpixB8n5n9i84Bf1uNlPLAIhAJviA-yh-FLB55CzFytm0u6T3m2RSahr1C_ySpt5VQcc&sharetype=gift&token=65fa760b-8441-4f3b-8bcf-ef312c85f3c5

2. Colorectal Cancer Foundation. Colorectal Cancer: New Data Suggest Rising Rates, More Advanced Disease in Young Adults. https://coloncancerfoundation.org/colorectal-cancer-new-data-suggest-rising-rates-more-advanced-disease-in-young-adults/#:~:text=While%20CRC%20in%20the%20general,people%20are%20on%20the%20rise.&text=The%20report%20projects%20that%20of,in%20individuals%20younger%20than%2050.

3. PubMed Central. Impact of Microplastics and Nanoplastics on Human Health. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920297/

4. Nature Reviews: Is early-onset cancer an emerging global epidemic? Current evidence and future implications. https://www.nature.com/articles/s41571-022-00672-8

5. Mayo Clinic. Cancer prevention: 7 tips to reduce your risk. https://www.mayoclinic.org/healthy-lifestyle/adult-health/in-depth/cancer-prevention/art-20044816

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About the Janssen Pharmaceutical Companies of Johnson & JohnsonAt Janssen, we're creating a future where disease is a thing of the past. We're the Pharmaceutical Companies of Johnson & Johnson, working tirelessly to make that future a reality for patients everywhere by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart. We focus on areas of medicine where we can make the biggest difference: Cardiovascular & Metabolism, Immunology, Infectious Diseases & Vaccines, Neuroscience, Oncology, and Pulmonary Hypertension. Learn more at https://www.janssen.com/southafrica.